Personal data

Place of Birth                                   Bologna, Italy

Date of Birth                                    17/03/1982

Citizenship                                       Italian

Telephone                                        +393271277869

E-mail                                               b.bonamassa@libero.it

 

Education/Degrees

 

2014 Master in Drug Regulatory Affairs. Italian Medicines Agency (AIFA) - La Sapienza University (Department of Physiology and Pharmacology Vittorio Erspamer), Rome – Italy. 110/110, magna cum laude. 

 

2009 PhD. Pharmacology and Toxicology. Alma Mater Studiorum - University of Bologna, Bologna – Italy. 

 

2006 Master degree in Molecular and Cellular Biology, Alma Mater Studiorum - University of Bologna, Bologna – Italy. 110/110, magna cum laude. 

 

2004  Bachelor’s degree in Biological Sciences. Alma Mater Studiorum - University of Bologna, Bologna – Italy. 110/110, magna cum laude. 

      

Working experience  

 

2015 I joined  Dr. Alvisi lab in June 2015, since then my research activity focuses on the study of the relationship between Hepatitis C Virus and infected Hepatocytes.

 

06/2015 Assegnista di Ricerca Senior, University of Padua; Department of Molecular Medicine

 

07/2014-present

Italian Medicines Agency (AIFA), Rome, Italy.

European Assessment Unit.
Internship.
Assessment of the Common Technical Document (CTD) for Registration of Pharmaceuticals for Human Use. 

 

12/2012-11/2013

Bambino Gesù Children’s Hospital, Piazza Sant’Onofrio 4, 00165 - State of Vatican City (extra-territory), Rome.

Department of Oncohematology, RNA editing laboratory. Post-doctoral research associate.

 

07/2011-09/2012

Fondazione Mario Negri Sud, Via Nazionale 8/A, 66030 - Santa Maria Imbaro, Chieti, Italy Department of Translational Pharmacology, Laboratory of Lipid Metabolism.
Post-doctoral research associate.

 

08/2009-06/2011

University of Pittsburgh, 3501 Terrace Street, Pittsburgh (PA), 15213 USA Department of Pharmaceutical Sciences, School of Pharmacy.
Visiting PhD student and post-doctoral research associate.

 

08/2009-06/2011

National Research Council (CNR), Via Moruzzi 1, 56100 - Pisa, Italy.
Institute of Clinical Physiology, Laboratory of Pharmacogenetics and Drug Metabolism. Visiting PhD student.

 

01/2007-12/2009

University of Bologna, Via Irnerio 48, 40125 – Bologna, Italia. Laboratory of Molecular Toxicology.
PhD student. 

 

Publications

 

1: Bonamassa, B., Ciccarese, F., Di Antonio, V., Contarini, A., Palù, G., and Alvisi, G. (2015) Hepatitis C virus and host cell nuclear transport machinery: a clandestine affair, Frontiers in Microbiology 6.

 

2: Canistro D, Boccia C, Falconi R, Bonamassa B, Valgimigli L, Vivarelli F, Soleti A, Genova ML, Lenaz G, Sapone A, Zaccanti F, Abdel-Rahman SZ, Paolini M. Redox-Based Flagging of the Global Network of Oxidative Stress Greatly Promotes Longevity. J Gerontol A Biol Sci Med Sci. 2014 Sep 4. pii: glu160. 

 

3: Feitelson MA, Bonamassa B, Arzumanyan A. The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease. Expert Opin Ther Targets. 2014 Mar;18(3):293-306. doi: 10.1517/14728222.2014.867947. Epub 2014 Jan 3. Review.

 

4: Tomaselli S, Bonamassa B, Alisi A, Nobili V, Locatelli F, Gallo A. ADAR enzyme and miRNA story: a nucleotide that can make the difference. Int J Mol Sci. 2013 Nov 19;14(11):22796-816. doi: 10.3390/ijms141122796. Review.

 

5: Bonamassa B, Moschetta A. Atherosclerosis: lessons from LXR and the intestine. Trends Endocrinol Metab. 2013 Mar;24(3):120-8. doi: 10.1016/j.tem.2012.10.004. Epub 2012 Nov 15. Review.

 

6: Bonamassa B, Ma Y, Liu D. Glucocorticoid receptor-mediated transcriptional regulation of N-acetyltransferase 1 gene through distal promoter. AAPS J. 2012 Sep;14(3):581-90. doi: 10.1208/s12248-012-9370-5. Epub 2012 May 30. 

 

7: Bonamassa B, Hai L, Liu D. Hydrodynamic gene delivery and its applications in pharmaceutical research. Pharm Res. 2011 Apr;28(4):694-701. doi: 10.1007/s11095-010-0338-9. Epub 2010 Dec 30. Review.

 

8: Bonamassa B, Liu D. Nonviral gene transfer as a tool for studying transcription regulation of xenobiotic metabolizing enzymes. Adv Drug Deliv Rev. 2010 Oct 30;62(13):1250-6. doi: 10.1016/j.addr.2010.08.005. Epub 2010 Aug 14. Review. 

 

9: Canistro D, Affatato AA, Soleti A, Mollace V, Muscoli C, Sculco F, Sacco I, Visalli V, Bonamassa B, Martano M, Iannone M, Sapone A, Paolini M. The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils. J Neurol Sci. 2010 Mar 15;290(1-2):90-5. doi: 10.1016/j.jns.2009.10.023. Epub 2009 Nov 28.

 

10: D'Aleo V, Del Guerra S, Martano M, Bonamassa B, Canistro D, Soleti A, Valgimigli L, Paolini M, Filipponi F, Boggi U, Del Prato S, Lupi R. The non-peptidyl low molecular weight radical scavenger IAC protects human pancreatic islets from lipotoxicity. Mol Cell Endocrinol. 2009 Oct 15;309(1-2):63-6. doi: 10.1016/j.mce.2009.05.010. Epub 2009 May 27. 

 

11: Granata G, Izzo T, Di Micco P, Bonamassa B, Castaldo G, Viggiano VG, Picillo U, Castaldo G, Niglio A. Thromboembolic events and haematological diseases: a case of stroke as clinical onset of a paroxysmal nocturnal haemoglobinuria. Thromb J. 2004 Nov 11;2(1):10. 

 

12: Sapone A, Bonamassa B, Canistro D, Pozzetti L, Paolini M. High-dose vitamin A. Lancet. 2007 Sep 1;370(9589):740.

 

13: Crochemore C, Virgili M, Bonamassa B, Canistro D, Pena-Altamira E, Paolini M, Contestabile A. Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis. Muscle Nerve. 2009 Apr;39(4):548-52. doi:10.1002/mus.21260.