Personal data

Place of Birth                                   Bologna, Italy

Date of Birth                                    20/02/1976

Citizenship                                       Italian

Telephone                                        +393282161733

E-mail                                               gualtiero.alvisi@unipd.it

 

Gualtiero Alvisi obtained his PhD Molecular and Cellular Biotechnologies from Bologna University, Italy in 2005, under the supervision of Dr. Alessandro Ripalti, working on the characterization of the nuclear import pathway of Human Cytomegalovirus DNA polymerase holoenzyme. During is PhD and his subsequent PostDoctoral studies he worked for 3 years in the group of Prof. David Jans, Department of Biochemistry and Molecular Biology at Monash University (Clayton, Victoria, Australia).

 

In 2007, he returned University of Bologna to continue his studies on Herpesviridae DNA polymerases under the supervision of Dr. Alessandro Ripalti, at the Department of Specialistic and Experimental Medicine.

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In 2009 he moved to University of Heidelberg to join the group of Prof. Ralf Bartenchlager at the Department of Molecular Virology to study the relationship between Dengue and Hepatitis C Virus and the host cell, focusing on the identification of host factors important for viral replication and lipid metabolism. 

 

In 2011 established his own research group at the Department of Molecular Medicine, University of Padova where he currently works as an Associate Professor of Microbiology and Clinical Microbiology.

 

The focus of Gualtiero's research is the relationship between infectious agents and infected cells, with particular attention to protein-protein interactions allowing virus replication and promoting disease establishment. 

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Current projects include the identification of small molecules disrupting protein-protein interactions important for Human Cytomegalovirus replication, exploitation of viral protease activity to sense viral infection and develop novel antivirals, and studies aiming at elucidating the role of nucleocytoplasmic transport in human diseases, including viral infections. More recently Gualtiero started to develop cellular sensors of viral proteases activity with to aim of developing new antivirals and diagnostic tools.

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Gualtiero collaborates with research groups within Italy (University of Bologna, University of Modena, University of Brescia) and internationally (Australia: Monash University, Canberra University, Wagga Wagga University, Heidelberg University) and his research is funded by PRIN and University of Padua research grants.

He is author of 53 scientific publications in peer-reviewed Journals, including Nature, Cell Host and Microbe Journal of Virology and FASEB, as well as two book chapters (Citations: 1856, h-index: 25). 

 

Gualtiero is also deeply involved in peer reviewing (https://publons.com/author/272395/gualtiero-alvisi#profile), being an Editor for PLOS ONE, SCIENTIFIC REPORTS and FRONTIERS IN MICROBIOLOGY as well as having reviewed for several Journals including Journal of Virology, Journal of Physiology, Biochemistry, Traffic, Analytical Chemistry, Frontiers in Microbiology, Viruses, Microorganisms and many others.